Veterinary Testing Platform

1. Inhalation anesthetics: Isoflurane.
2. Injectable anesthetics: Zoletil 50, Seraquin (Xylazine), Propofol injection, Lidocaine hydrochloride injection, Procaine hydrochloride injection, Avertin.
3. Analgesics: Meloxicam injection.

Application method: Please apply through the Hong Kong University of Science and Technology (Guangzhou) Large Instrument Sharing Management Platform at https://instrumentsharelab.hkust-gz.edu.cn/.

Usage instructions:Isoflurane: Induction anesthesia 3.0-5.0%, Maintenance anesthesia 1.5-3.0%

1. Fill out the form "F-AM-001-V1 Animal Purchase and Animal Facility Application Form" and submit it via email. The Central Laboratory of Experimental Animals generally arranges for animal reception on Wednesdays and Fridays. Applications for animals to be received on Wednesday should be submitted by the previous Friday, and applications for animals to be received on Friday should be submitted by the Wednesday of that week.

2.Once the staff receives the application, they will respond via email regarding whether the animals can be accepted and recommend suitable housing arrangements based on the quality of the animals.

3.Upon receiving the animals, the animal caretakers will verify the animal information (including strain, ID number, sex, birth date, quantity, etc.) and assess the condition of the animals. If there are any discrepancies with the application form or if the animals show abnormalities, the applicant will be notified via email.

4.Adaptation and quarantine period: The staff will develop an adaptation and quarantine plan based on the condition of the animals and will respond via email. Experiments can only be conducted on the animals after the adaptation and quarantine processes are complete.

5.If the incoming animals require purification, prior contact must be made with the Embryo Transfer and Purification Platform.

6.If animals are being brought in from non-production units (such as universities or research institutes), the provider must submit a "Mouse Health Report" or "Animal Quality Inspection Report" for the room where the animals were kept for the last three months. Detailed quarterly animal quality inspection reports are preferable.

The quarantine period generally takes 10 working days. Please arrange the purchase of animals in advance according to your experimental plan. If time is tight, you can communicate with the veterinarian in detail, or purchase animals from a trusted supplier. The experiment can be carried out after the 3-day adaptation period.

If experimental animals need to take out the barrier, they must apply with the veterinarian in advance and fill out the "Animal Removal from Animal Facility Record Form". After the experiment is completed, animals that have not been killed must return to the LAF temporary storage area within 24 hours. Experimental animals are not allowed to be kept in areas outside the LAF for more than one day; if they have been killed, take the animal carcass back to the waste temporary storage room and fill in the "Animal Carcass Storage and Processing Record".

The current cleanliness management requirements for the LAF experimental area are: Area C > Area B/A > Area D/E > Area F/L1. Area C/B/A is the highest level. In principle, if you enter other areas on the same day, you are not allowed to enter Area C/B/A again. Therefore, within the same day, after entering the F area/L1 area experiment, you are not allowed to enter other barrier areas. Users are requested to reasonably arrange the entry sequence and entry time according to the experimental needs.

Some strains of mice are aggressive by nature. If you find fighting in the cage, please pick out the strongest one (with no injuries and intact beard) and keep it in a separate cage. If you find animals with abnormal conditions such as alopecia areata, malocclusion, severe trauma or large lumps, please notify the LAF breeder and veterinarian and fill in the F-VET-008 "Laboratory Animal Abnormal Handling Record Form". The veterinarian and the project leader will discuss and take appropriate measures for the animals.

No need, the first report of the World Health Organization's WHO Rabies Expert Consultation specifically mentioned that "rodents are not storage hosts for the disease" and "specialized post exposure prophylaxis against rabies is rarely required after exposure to rodents, rabbits, and wild rabbits." This means that being bitten by mice usually does not require vaccination against rabies.
When a person is bitten, scratched by an animal, or injured by a sharp object, the following steps should be taken:
Immediately clean the wound: Rinse the wound thoroughly with water and hand soap (or soap) for about 15 minutes to reduce the risk of infection.
Disinfect the wound: After cleaning, use iodine, 75% alcohol, or hydrogen peroxide to disinfect the wound and further kill any potential pathogens.
Bandage the wound: Cover the wound with clean gauze or a bandage to avoid secondary contamination.
Monitor the wound: If signs of infection such as redness, swelling, increased pain, fever, or discharge appear, seek medical attention immediately.
Note: If the wound is deep or bleeding heavily, go directly to the hospital for treatment and avoid improper self-handling.